Live Updates

Recent R&D and ongoing trials.

High-signal developments in stroke care — new trial results, important ongoing studies, and early signals worth watching. These are brief notes, not full analyses.

Educational summaries only

These notes are for awareness. Always go to primary sources and guidelines before changing practice.

Active & Upcoming

What to watch in 2026–2027.

Phase 3 • Expected 2026

TENSION — Tenecteplase in large-core ischemic stroke

Question

Can TNK safely extend thrombolysis benefit into large-core patients?

Status & Why It Matters

One of the most important ongoing trials for expanding reperfusion eligibility. Positive results would meaningfully change practice for a currently underserved population.

Long-term follow-up • 2026

SELECT2 extended outcomes

Question

What do large-core thrombectomy patients look like at 1 year and beyond?

Status & Why It Matters

Will help answer whether the early benefit seen in SELECT2 holds up, and how we should counsel families.

Registry • Ongoing

MR CLEAN LATE real-world data

Question

How does late-window thrombectomy perform outside of trial centers?

Status & Why It Matters

Post-marketing European registry. Will show whether the benefits seen in trials translate to routine practice.

Multiple Phase 3 • 2026–2027

GLP-1 receptor agonists & stroke prevention

Question

Do the new weight-loss / diabetes drugs meaningfully reduce stroke risk?

Status & Why It Matters

Several large cardiovascular outcome trials with dedicated stroke endpoints are reading out. Could become an important secondary prevention tool.

This page is fed by our automated daily research digest (PubMed + ClinicalTrials.gov). Every week we also generate a **"This Week in Stroke"** summary for quick reading. All content is human-reviewed before publishing. For deeper analysis, see the full articles and the Trial Library.